(5S)-5-(AMinoMethyl)-3-[3-fluoro-4-(4-Morpholinyl)phenyl]-2-oxazolidinone
(S)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]amine
CAS: 168828-90-8
Molecular Formula: C14H18FN3O3
(5S)-5-(AMinoMethyl)-3-[3-fluoro-4-(4-Morpholinyl)phenyl]-2-oxazolidinone - Names and Identifiers
(5S)-5-(AMinoMethyl)-3-[3-fluoro-4-(4-Morpholinyl)phenyl]-2-oxazolidinone - Physico-chemical Properties
| Molecular Formula | C14H18FN3O3 |
| Molar Mass | 295.31 |
| Density | 1.319 |
| Melting Point | 95-97°C |
| Boling Point | 480.0±45.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | Off-White to Pale Yellow |
| pKa | 8.96±0.29(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
(5S)-5-(AMinoMethyl)-3-[3-fluoro-4-(4-Morpholinyl)phenyl]-2-oxazolidinone - Risk and Safety
| HS Code | 2934990002 |
(5S)-5-(AMinoMethyl)-3-[3-fluoro-4-(4-Morpholinyl)phenyl]-2-oxazolidinone - Introduction
(S)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]amine, also known as Fmoc amino protectant, it is a protecting group commonly used in chemical synthesis.
In terms of properties, Fmoc amino protectant is white or off-white crystalline powder with high melting point and solubility. It is soluble in organic solvents, but insoluble in water.
The main purpose of the Fmoc amino protecting agent is to protect the amine group in organic synthesis. It can be removed by a nucleophile (such as an alkaline reagent) similar to dicyclopentadiene, thereby restoring the amine group. Therefore, it is widely used in peptide synthesis, drug synthesis and polymer synthesis.
In terms of the preparation method, the Fmoc amino protecting agent is usually prepared by reacting aniline with 3-fluoro-4-morpholinoformate to obtain a precursor compound, and then reacting the precursor with phthalimide to obtain the target compound. The preparation of Fmoc amino protectors requires certain chemical synthesis techniques and equipment.
In terms of safety information, Fmoc amino protectants have low toxicity under normal operating conditions. However, proper laboratory practices, including the wearing of appropriate personal protective equipment (e. G., lab gloves, safety glasses, etc.) must be followed during handling and use. And ensure a well-ventilated operating environment. In addition, care should be taken when storing and handling solids and solutions of the compound to prevent contact with oxygen, light and heat to avoid unnecessary decomposition and hazards.
To sum up, Fmoc amino protectant has certain properties and uses, and is a commonly used chemical reagent, but it is necessary to pay attention to the relevant preparation methods and safety measures when using it.
In terms of properties, Fmoc amino protectant is white or off-white crystalline powder with high melting point and solubility. It is soluble in organic solvents, but insoluble in water.
The main purpose of the Fmoc amino protecting agent is to protect the amine group in organic synthesis. It can be removed by a nucleophile (such as an alkaline reagent) similar to dicyclopentadiene, thereby restoring the amine group. Therefore, it is widely used in peptide synthesis, drug synthesis and polymer synthesis.
In terms of the preparation method, the Fmoc amino protecting agent is usually prepared by reacting aniline with 3-fluoro-4-morpholinoformate to obtain a precursor compound, and then reacting the precursor with phthalimide to obtain the target compound. The preparation of Fmoc amino protectors requires certain chemical synthesis techniques and equipment.
In terms of safety information, Fmoc amino protectants have low toxicity under normal operating conditions. However, proper laboratory practices, including the wearing of appropriate personal protective equipment (e. G., lab gloves, safety glasses, etc.) must be followed during handling and use. And ensure a well-ventilated operating environment. In addition, care should be taken when storing and handling solids and solutions of the compound to prevent contact with oxygen, light and heat to avoid unnecessary decomposition and hazards.
To sum up, Fmoc amino protectant has certain properties and uses, and is a commonly used chemical reagent, but it is necessary to pay attention to the relevant preparation methods and safety measures when using it.
Last Update：2024-04-09 21:50:46
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Product Name: Linezolid Impurity 4 Monomer Visit Supplier Webpage Request for quotationCAS: 168828-90-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Deacetyl Linezolid Visit Supplier Webpage Request for quotationCAS: 168828-90-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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